Isaac N. Vannuys was born in Franklin Township, Johnson County, April 30, 1830, being the second in a family of ten children born to Samuel and Anna (List) Vannuys; the former born in Shelby County, Ky., in 1803, the latter a native of the same state, and died in this county at an advanced age. The family came to this county in a very early day. Our subject was a student at the Hopewell school-house. Mr. Vannuys makes farming and stock-raising his principal employment, and by industry and good management, has secured a valuable farm comprising ninety acres of well-improved land, which he purchased in the spring of 1862. He was married in February, 1852, to Miss Minerva A. Lagrange, born in Franklin Township, April 25, 1833, daughter of Peter D. and Patsy (Ransdall) Lagrange. To the above marriage are these three children: Mattie, born November 10, 1860; Emma V., January 22, 1865, and Samuel W., November 7, 1866. In politics, Mr. Vannuys is an active republican, and since 1845, has been a member of the Hopewell Presbyterian Church. Mrs. Vannuys became a member of the same church in 1848. He is an honest, upright citizen, esteemed for his many good qualities by all who know him.